In 2017, she was announced to play the female lead of the film adaptation of the Mark Burnell novel The Rhythm Section, produced by Barbara Broccoli and Michael G. In 2012 Lively's wedding reception was featured in Martha Stewart Weddings; food photography was the focal point of the picture spread.
Lively and Penn Badgley appeared in a pro-Obama commercial, as part of Move On.org's Youth Vote program.
She appeared in the film adaptation of the novel of the same name, The Sisterhood of the Traveling Pants, in 2005, as Bridget, one of the four female leads.
Lively's performance in the film earned her a nomination for a Teen Choice Award for "Choice Movie Breakout – Female.
In 2006, Lively co-starred with Justin Long in Accepted, and Lively had minor roles in the horror film, Simon Says.
While Accepted was not well received by critics, Lively's performance was, earning her a 'Breakthrough Award' from Hollywood Life.